While triggering different bots within the same topic will not be possible, you can always choose to trigger or not trigger a custom bot in or outside Business Hours. You can enable this setting under Topics  > Select the name of the Topic > Trigger bot flow and configure the trigger of the bot according to the requirement from the 3 options available namely:

1. Inside (To trigger the bot within the business hours)

2. Outside (To trigger the bot outside the business hours)

3. Both (To trigger the bot both outside and inside the business hours)